Assistant Professor, Department of Ophthalmology Wayne State University School of Medicine Kresge Eye Institute Specialty: LASIK, Refractive Surgery, and Cataract Surgery Medical School: Wayne State University School of Medicine Residency: Kresge Eye Institute Appointment Locations: Detroit and Troy Board Certification: American Board of Ophthalmology Clinical Interests: LASIK, PRK, Refractive and Complex Cataract Surgery Hobbies: Cooking, Guitar, Amaro Publications: Mishulin A, Arsenault S, Glybina I, Tomsak RL. Reversible retinoschisis following high voltage electrical injury evaluated with optical coherence tomography and electrophysiology. Am J Ophthalmol Case Rep. 2020;19:100760. Keen JA, Kennedy BJ, Mishulin A, et al. Adult Versus Pediatric Relapse and Recurrence in Orbital Inflammatory Syndrome. Ophthalmic Plast Reconstr Surg. 2020 Winker KP, Beaulieu R, Bevill L, Mishulin A, Black EH. Effects of Aspirin on Postoperative Bruising and Bleeding Complications in Upper Eyelid Surgery. Ophthalmic Plast Reconstr Surg. 2020 Mishulin, Aleksey MD; Gandhi, Sachin BA; Apple, Daniel MD; Lin, Xihui MD; Hu, Jonathan MD; Abrams, Gary W. MD: Inducible Transient Central Retinal Artery Vasospasm: A Case Report. Retinal Cases and Brief Reports; September 2017
Assistant Professor, Department of Ophthalmology Wayne State University School of Medicine Kresge Eye Institute Specialty: Vitreoretinal Surgery Medical School: University of Washington School of Medicine Residency: Ophthalmology, Kresge Eye Institute/ Wayne State University Fellowship: Retina, University of California, Davis Appointment Locations: Detroit, Taylor, and Troy Board Certification: American Board of Ophthalmology Clinical Interests: Age-related Macular degeneration, Diabetic Retinopathy, Retinal detachment, Retinal Vascular Disease, Macular Pucker and Macular Hole
Department of Ophthalmology and Anatomy/Cell Biology
Wayne State University School of Medicine
Kresge Eye Institute
Specialty: Cataract, Dry Eye Disease, Comprehensive Ophthalmology
Medical School: Albert Einstein College of Medicine, Yeshiva University
Residency: Ophthalmology, Henry Ford Hospital, Detroit, Michigan
Fellowship: National Institutes of Health, Bethesda, MD
Appointment Locations: Bingham Farms and Detroit
Board Certification: American Board of Ophthalmology
Clinical Interests: Cataract surgery, dry eye diease, diabetic eye exams, macular degeneration, inflammatory eye diseases, glaucoma, external eye diseases
Research Interests: Developing thymosin beta 4 as a novel therapy for corneal wound healing, inflammation, and dry eye disease
Special Activities: Member, American Academy of Ophthalmology; Member, Association for Research in Vision and OphthalmologyHonors:
2011 AFER/Pfizer Ophthalmics Carl Camras Translational Research Award, ARVO, May 1, 2011, Fort Lauderdale, FL.
2012 Voted to Top Doctors Metro Detroit
2012 Top Ophthalmologist, International Association of Ophthalmologists
2013 Voted to Best Doctors of America
2014 Voted to Best Doctors of America
Sosne G, Ousler GW. Thymosin β4 Ophthalmic Solution for Dry Eye: A Randomized, Placebo-Controlled Phase 2 Clinical Trial Conducted Using the Controlled Adverse Environment (CAE™) Model. Expert Opinion. In revision.
Sosne G, Kim C, Kleinman HK. Thymosin β4 Significantly Reduces the Signs of Dry Eye in a Murine Controlled Adverse Environment Model of Experimental Dry Eye. Expert Opinion. In press.
Sosne G, Dunn SP, Kim C. Thymosin beta 4 Significantly Improve Signs and Symptoms of Severe Dry Eye in a Phase 2 Clinical Trial. CORNEA In press.
Sosne G, Qiu P, Ousler GW 3rd, Dunn SP, Crockford D. Thymosin β4: a potential novel dry eye therapy. Ann N Y Acad Sci. 2012 Oct;1270:45-50. doi: 10.1111/j.1749-6632.2012.06682.x.
Goldstein, AL, Hannappel E, Sosne G, Kleinman HK. Thymosin β4: A Multi-Functional Regenerative Peptide Basic Properties and Clinical Applications. Expert Opin Biol Ther. 2012 Jan;12(1):37-51. Epub 2011 Nov 10.
Qiu P, Wheater MK, Qiu Y, Sosne G. Thymosin beta 4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK. FASEB J. 2011 Feb 22, [Epub ahead of print]
Dunn SP, Heidemann DG, Chow CYC, Crockford D, Turjman N, Angel J, Allan CB, and Sosne G. “Treatment of Chronic Non-Healing Neurotrophic Corneal Epithelial Defects with Thymosin 4”
Ann N Y Acad Sci. 2010 Apr;1194:199-206. Dunn, SP, Heidemann DG, Chow CY, Crockford D, Turjman N,Angel, J, Allan CB, Sosne G. Arch Ophthalmol. Treatment of Chronic Nonhealing
Neurotrophic Corneal Epithelial Defects With Thymosin Beta 4. 2010 May; 128(5):636-8. Sosne G, Qiu P, Goldstein AL, Wheater MK. Biological activities of thymosin beta 4 defined by active sites in short peptide sequences. FASEB J. 2010 Jul;24(7):2144-51. Epub 2010 Feb 23. Sosne G, Qiu P, Christopherson PL, Wheater MK. Thymosin beta 4 suppression of corneal
NFkappaB: A potential anti-inflammatory pathway. Exp Eye Res. 2007 Apr;84(4):663-9. Gabriel Sosne, M.D.
The David Barsky, M.D. Endowed Chair
Professor and Chairman, Department of Ophthalmology Wayne State University School of Medicine
Director, Kresge Eye Institute
Medical School: Wayne State University School of Medicine
Residency: Ophthalmology, Kresge Eye Institute, Wayne State University School of Medicine, Detroit, Michigan
Fellowship: Glaucoma, Wilmer Eye Institute, Johns Hopkins University
Appointment Locations: Detroit, Southfield, Taylor and Troy
Board Certification: American Board of Ophthalmology
Clinical Interests: Glaucoma and cataracts
Research Interests: Surgical and pharmaceutical clinical trials, socioeconomics of ophthalmology, educational research
Special Activities: Associate Dean, GME, Wayne State University; Vice President, Academic Affairs, Detroit Medical Center; Member, Ophthalmology Residency Review Committee, ACGME
Honors: ACGME Parker J. Palmer “Courage to Teach” award, Best Doctors in America